Biotechnology

Examples of treated products: Permeation solutions, sterile solutions, …

Combined mastery of boilerworks and mobile agitation units makes GOAVEC Engineering one of the main suppliers of pharmaceutical boilerworks that comply with ASME-BPE (Association of Mechanical Engineering – Bioprocess Engineering) recommendations.

MOBILE TANKS

Product description:

  • Storage and transfer of liquid or paste-like products
  • Tanks with capacities of up to 1,000 litres are manufactured in our workshops
  • Operating conditions in accordance with customers’ needs: Atmospheric, ultra-clean, and sterile conditions (Pressurised Equipment Directive)
  • Agitation defined depending on the rheological characteristics of the product
  • Magnetic drive or standard throughput drive
  • Specific equipment items developed such as transfer trolleys for autoclave tanks
  • ATEX zoning factored in
  • Tight metallurgical control of the specific characteristics desired: Various grades of stainless steel, ferrite rate, roughness Ra of 0.2 μm, etc …
  • Design and manufacturing in accordance with the company QAP, and the PQP (Project Quality Plan) (FAT/SAT, IQ/OQ).

STORAGE TANKS

Product description:

  • Storage of liquid or paste-like products
  • Tanks with capacities of up to 300,000 litres are manufactured in our workshops
  • Operating conditions in accordance with customers’ needs: Atmospheric, ultra-clean, and sterile conditions (Pressurised Equipment Directive)
  • Agitation defined depending on the rheological characteristics of the product
  • Magnetic drive or standard throughput drive
  • Specific equipment items developed for cleanability, ATEX decommissioning
  • ATEX zoning factored in
  • Tight metallurgical control of the specific characteristics desired: Various grades of stainless steel, ferrite rate, roughness Ra of 0.2 μm, etc …
  • Design and manufacturing in accordance with the company QAP, and the PQP (Project Quality Plan) (FAT/SAT, IQ/OQ)

Examples of treated products: Purified water storage, water for injection, …

Examples of treated products: Yeasts, bacteria, enzymes, cells, biomass, …

FERMENTATION TANKS/BIOREACTOR

Product description:

  • Specific tanks which can be sterilised in place enabling microbial and cell cultures for your products in a GMP environment in accordance with batch and continuous fed-batch supply methods. Checking of the key fermentation parameters – 0°, pH, aeration, etc …
  • Tanks with capacities of up to 40,000 litres are manufactured in our workshops
  • Agitation defined depending on the rheological characteristics of the product and enabling high yields in terms of oxygenation and thermal performances
  • Specific equipment items developed for cleanability and aeration (sparger)
  • Design and manufacturing in accordance with the Goavec Engineering PQP (Project Quality Plan) (FAT/SAT, IQ/OQ)

CULTURE MEDIA PREPARATION TANKS

Product description:

  • Specific tanks which can be sterilised on site enabling culture media to be prepared and kept homogeneous
  • Tanks with capacities of up to 50,000 litres are manufactured in our workshops
  • Agitation defined depending on the characteristics of the product (density, viscosity) and ensuring effective mixing of the medium
  • Specific equipment items developed for cleanability and incorporating raw materials
  • Design and manufacturing in accordance with the Goavec Engineering PQP (Project Quality Plan) (FAT/SAT, IQ/OQ).

SKIMMING AND INACTIVATION TANKS

Product description:

  • Specific tanks which can be sterilised in place enabling skimming and inactivation of the products’ active principles
  • Tanks with capacities of up to 20,000 litres are manufactured in our workshops
  • Agitation defined depending on the characteristics of the product (density, viscosity) and ensuring effective mixing of the product
  • Specific equipment items developed for cleanability
  • Design and manufacturing in accordance with the Goavec Engineering PQP (Project Quality Plan) (FAT/SAT, IQ/OQ).

TURNKEY FERMENTATION PLATFORMS

Goavec Engineering designs and executes:

  • Storage and distribution of bulk raw materials
  • Systems for purified water and water for injection
  • Clean fluids distribution (sterile air, nitrogen, pure steam, etc…)
  • Culture media preparation skids
  • Pilot fermentation tanks
  • Fermentation installations
  • Storage and distribution of related products
  • CIP / SIP station
  • The electrical and automatic control systems architectures

Examples of products treated by our teams:

  • Enzymes
  • Yeasts
  • Bacteria
  • Cell cultures for vaccines
  • Antibiotics
  • Monoclonal antibodies
  • Growth hormones…